Nine contemporary therapeutic directions in heart failure
نویسندگان
چکیده
منابع مشابه
Beta-blockers in heart failure. Future directions.
The rationale for beta-blockade in heart failure is now well established. Heart failure mortality, which is predicted by neurohormonal activation, remains high despite modern treatment including ACE inhibition, and additional neurohormonal blockade has further therapeutic potential. Previous clinical trial experience in heart failure, most of which has been in patients with idiopathic cardiomyo...
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From the *Heart Pittsburgh Schoo Cardiomyopathy C California; zCente School of Medici University, Atlanta Siemens; has receiv purposes; and has r The Pittsburgh F GlaxoSmithKline, Relypsa, Scios, St. as the Eliot Cord Ahmanson Found ew therapeutic targets, agents, and strategies are needed to prevent and treat heart failure (HF) after a decade of failed research efforts to improve long-term pat...
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Pharmacological therapy of systolic left ventricular dysfunction has evolved over the past 3 decades. Current therapy is focused primarily on the regulation of the renin-angiotensin-aldosterone axis and sympathetic nervous system. Additional targets of pharmacotherapy include vasoconstriction, impaired nitric oxide metabolism, inflammation and improving myocardial function. As therapies in chro...
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This is the second of a 2-part review of heart failure in children. In Part I, we focused on history, definition, etiology, and pathophysiology.1 In Part II, we review diagnosis, treatment, and future directions. The intention is to highlight key concepts and trends, with the goal of stimulating further interest in research to support evidence-based treatment in pediatric cardiovascular disease.
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ژورنال
عنوان ژورنال: Heart Asia
سال: 2019
ISSN: 1759-1104
DOI: 10.1136/heartasia-2018-011150